Asthma

Chronic inflammatory airway disease causing wheezing, breathlessness and chest tightness. Prescribed controller and rescue inhalers are the treatment. Managing weight and avoiding known triggers can help alongside them; vitamin D supplements have not been shown to prevent attacks3.

Respiratory Evidence-Based

Last updated:

โš ๏ธ Medication safety: please read first. The nutrition and supplement approaches on this page are meant to work alongside your prescribed treatment, never to replace it. Never stop, reduce or change your asthma medication, including preventer inhalers, without your prescriber's guidance. Doing so can be dangerous. Some supplements interact with asthma medication or can trigger an attack, so talk to your prescriber or pharmacist before starting anything on this page.

What Is Asthma?

Asthma is a chronic inflammatory disease of the airways causing reversible bronchoconstriction, mucus hypersecretion and airway hyperresponsiveness. Hallmark symptoms (wheezing, breathlessness, chest tightness, cough) result from narrowed, inflamed airways and twitchy smooth muscle.

Modern understanding identifies multiple asthma "phenotypes": allergic/​eosinophilic (Th2-⁠high, about half of people with mild to moderate asthma in one study10), non-allergic, exercise-induced, aspirin-exacerbated and obesity-associated. Each responds differently to treatment: biologics6 target specific Th2 pathways, while obesity-related asthma improves with weight loss.

The gut-lung axis is an active area of research in asthma. Children given antibiotics in their first 3 years were more likely to develop asthma in cohort studies, an association rather than proof of cause, and no gut treatment is established for asthma11. In trials, vitamin D supplements did not reduce asthma attacks3.

โš ๏ธ NEVER discontinue prescribed asthma controllers1 (inhaled corticosteroids) without medical guidance, even when feeling better. Uncontrolled asthma can be fatal. Use holistic approaches IN ADDITION to controllers; aim to reduce reliance on rescue inhalers, not replace controllers.
Two airways in cross-section: a normal airway (wide open) and an asthma airway narrowed by tightened muscles, a swollen wall and mucus, above four faces showing coughing, wheezing, shortness of breath and chest tightness

Major Asthma Phenotypes

Allergic/​Eosinophilic

Th2-⁠driven. Triggered by allergens (dust mites, pollen, pet dander). Elevated IgE, eosinophils. Responds well to inhaled steroids; severe cases benefit from biologics (omalizumab, mepolizumab, dupilumab).

Non-Allergic / Exercise-Induced

Often adult-onset when non-allergic; exercise-induced symptoms occur at any age. Triggered by infection, cold air, exercise, stress, irritants. Often less responsive to steroids. Vagal/​autonomic factors. Breathing exercises may improve quality of life8.

Obesity-Associated

Adult-onset, often in women. Driven by metabolic inflammation, mechanical restriction. Less Th2-⁠eosinophilic. Often improves with weight loss.

Asthma by the Numbers

27.8 million
people in the US with current asthma in 2023, 8.4% of the population18
About 1 in 11
US adults with current asthma in 2023 (8.9%)18
3,624
asthma deaths in the US in 2023 18
$81.9 billion
total US cost of asthma in 2013, counting medical care, missed work and school days, and deaths19
363 million
people worldwide with asthma in 2023; it caused 442,000 deaths20
20 trials
in a 2023 review, vitamin D did not reduce asthma attacks needing steroid tablets or improve asthma control3

Symptoms of Asthma

Symptoms wax and wane and are often worse at night/​early morning. Recognize warning signs of exacerbation early; they can progress to life-threatening attacks.

SymptomWhat happens
Typical Daily Symptoms
WheezingHigh-pitched whistling sound during breathing (usually exhalation). Caused by airflow through narrowed bronchi. May be subtle or loudly audible.
Shortness of BreathSensation of inability to breathe deeply. Worsens with exertion, exposure to triggers. Difficulty completing sentences in severe attacks.
Chronic CoughOften the only symptom in "cough-variant asthma." Worse at night, with exercise or after viral infections. Sometimes productive of clear mucus.
Chest TightnessSensation of band around chest. Caused by bronchial smooth muscle constriction. May be mistaken for cardiac chest pain.
Severe Attack (Emergency)
Inability to Complete SentencesSingle words between breaths. Sign of severe airflow obstruction. Call 911 now, and use your rescue inhaler while you wait.
Use of Accessory MusclesVisible neck/chest muscles working hard with each breath. Tripod position (leaning forward, hands on knees). Indicates respiratory distress.
Cyanosis (Blue Lips/Fingers)Bluish tinge of lips, fingertips. Sign of hypoxia. LIFE-THREATENING, call 911 immediately.
Silent ChestPARADOXICAL: in severe attack, wheezing may disappear as airflow is too low to produce sound2. Most ominous sign. 911 immediately.

Causes of Asthma

It is not fully understood what causes asthma15; these are the factors with the clearest links, and the things that set off symptoms once it has started.

CauseHow It Contributes to AsthmaWhat Helps
Family history and allergiesAsthma is more likely when a parent or sibling has it, and in people with other allergic conditions20A preventer inhaler taken as prescribed, and allergy testing where a trigger is suspected, as the diagnosis section describes
Allergens and irritants at home and at workHouse dust mites, molds, pollen, animal fur, smoke and fumes set off symptoms, and chemicals, fumes or dust at work can cause asthma20Reducing exposure to your own triggers, as the treatment section describes, and moving away from a trigger at work
Tobacco smoke and air pollutionTobacco smoke and air pollution in early life raise the risk of asthma20, and smoking or breathing secondhand smoke makes asthma harder to treat21Stopping smoking and avoiding secondhand smoke and vaping, as the treatment section lists
Chest infectionsViral respiratory infections in early life raise the risk of developing asthma20, and viruses such as flu make symptoms worse at any age15The yearly flu vaccine the treatment section lists, and your written action plan when symptoms flare
Excess weightChildren and adults with overweight or obesity are at greater risk of asthma20; in trials in adults with obesity and asthma, weight loss over 12 to 24 weeks improved asthma control and lung function22Gradual weight loss, as the treatment and diet sections describe; in the trials the benefit had faded by a year, so it lasts only while the weight stays off
Early life: prematurity, low birth weight, early antibioticsPrematurity and low birth weight raise the risk20; children given antibiotics in their first 3 years were more likely to develop asthma in cohort studies, an association rather than proof of cause11Nothing on this page changes early-life risk; once asthma is present, the preventer inhaler and trigger control are what help
Certain medicinesSome anti-inflammatory painkillers and beta blockers can set off asthma symptoms in some people15Checking with a pharmacist or doctor before taking a medicine for another condition; never stop a prescribed medicine on your own

How Asthma Is Diagnosed

TestWhat it shows
Pulmonary Function Testing
Spirometry (Gold Standard)Measures FEV1 (forced expiratory volume) and FVC. In adults, a rise in FEV1 or FVC of 12% and 200 mL after a bronchodilator supports an asthma diagnosis9. It is the main test used to confirm asthma, though tracking peak flow over two weeks or a challenge test can also confirm it.
Peak Flow MonitoringDaily home monitoring of peak expiratory flow. Track personal best, recognize drops indicating impending exacerbation. Useful for self-management plans.
Methacholine ChallengeUsed when spirometry normal but asthma suspected. Inhalation of methacholine triggers bronchoconstriction in asthmatics. Negative test rules out asthma.
FeNO (Exhaled Nitric Oxide)Marker of eosinophilic airway inflammation. Elevated FeNO predicts steroid-responsive asthma. Useful for phenotyping and treatment selection.
Phenotyping & Trigger ID
CBC with Eosinophil CountAn eosinophil count of 300 cells/ยตL or more indicates the eosinophilic phenotype. Important for biologic therapy selection. Total IgE level also informative.
Allergy TestingSkin prick tests or specific IgE blood tests. Identify triggers: dust mites, pet dander, cockroaches, molds, pollens, foods. Guides avoidance and treatment.
Vitamin D LevelLow vitamin D correlates with worse asthma control and more exacerbations; a level is checked where deficiency is suspected.
Asthma Control Tools (ACT, ACQ)Validated questionnaires for assessing control over preceding weeks. An ACT score below 20 suggests asthma is not well controlled26. Track over time.

Conventional and Holistic Treatment for Asthma

๐ŸŒฟ HOLISTIC
๐Ÿ’Š CONVENTIONAL
๐ŸŒฟ

Holistic / Functional Approach

Reduce inflammation and identify triggers; the gut-lung axis is being studied, with no gut treatment established. ALWAYS used WITH (not instead of) controllers.

Trigger Avoidance5
Identify and reduce exposure to dust mites, mold and pet dander, and avoid foods only where an allergy is confirmed
Anti-Inflammatory
A diet high in fruit and vegetables is linked with better control4; vitamin D supplements did not prevent attacks in trials3; omega-⁠3 trials have been largely disappointing4
Breathing Retraining
Buteyko, diaphragmatic and similar breathing exercises may improve quality of life and hyperventilation symptoms, with moderate to very low-certainty evidence8
Gut-Lung Axis
Being studied; probiotics gave a small lung function benefit in trials, not enough for routine use11

Full Holistic Approach Includes

  • Identify triggers: dust mite encasings, HEPA filter, remove pets if allergic, mold remediation
  • Avoid dairy only if you have a confirmed milk allergy.
  • If a food seems to set off symptoms, ask about allergy testing, for example for wheat, eggs, soy or peanuts, rather than cutting foods out on your own.
  • Vitamin D: set the dose with your clinician; most adults need no blood test first. A 2023 review of 20 trials found it did not reduce asthma attacks, so correct a deficiency for general health, not as asthma treatment3. Dosing limits: the adult tolerable upper intake level is 4,000 IU/day. The Endocrine Society's 2024 guideline found no clear evidence for an optimal target level; the National Academies (formerly the Institute of Medicine) set sufficiency at 20 ng/mL (50 nmol/L). Any dose above 4,000 IU/day needs a blood test and a clinician.
  • Omega-⁠3 EPA/DHA 2,000 to 3,000 mg/day, agreed on with your clinician (see the supplement table); trials in asthma have been largely disappointing4, and check with your clinician first if you take a blood thinner7
  • Magnesium, not recommended: oral magnesium did not reduce reliever use or symptoms in trials, and magnesium given into a vein in the hospital for a severe attack is a different treatment that says nothing about tablets.4 The upper intake level for supplemental magnesium is 350 mg/day; above that, diarrhea is common. With kidney disease, take it only on your clinician's advice.
  • Mediterranean diet, vegetables, fruits, fatty fish, olive oil.
  • Address obesity: weight loss improves asthma control in the obesity-associated phenotype
  • Buteyko breathing retraining may improve quality of life and hyperventilation symptoms
  • Avoid sulfites (wine, dried fruits) if they trigger symptoms
  • Stop smoking and avoid secondhand smoke, one of the most useful steps; vaping is also harmful.
  • Annual flu vaccine and COVID-⁠19 boosters: viral infections are major triggers
โš ๏ธ Critical Safety Note: NEVER stop your controller inhaler without medical supervision, even when feeling perfectly fine. Asthma deaths often occur in patients who felt well and discontinued controllers. Use holistic approaches to add benefit, not replace life-saving medications.

Evidence-Based Supplements for Asthma

No supplement replaces a preventer inhaler, and in trials vitamin D did not reduce attacks3. Use alongside (not instead of) prescribed controllers.

SupplementWhat it is forTypical rangeTimingNotes & cautions
Vitamin D3Did not reduce attacks needing steroid tablets or improve control in a 2023 review of 20 trials3. Worth correcting a deficiency for general health.Set the dose with your clinician; most adults need no blood test firstWith fat mealPair with K2 200 mcg. If you take warfarin, clear any vitamin K supplement with the clinician managing your anticoagulation before starting or stopping it: vitamin K antagonizes warfarin, and changing your intake destabilizes the INR. Consistency matters more than avoidance. This does not apply in the same way to direct oral anticoagulants such as apixaban or rivaroxaban, but tell your prescriber about any supplement you take.
Omega-⁠3 (EPA/DHA)Anti-inflammatory; reduces leukotrienes. May reduce exercise-induced bronchoconstriction.2,000 to 3,000 mg EPA+DHA/dayWith fat mealTrials in asthma have been largely disappointing4. If you take a blood thinner, agree on it with your clinician first, since clotting may need monitoring7. In heart trials, fish oil supplements raised the risk of atrial fibrillation, an irregular heartbeat, more so above 1 g a day25, so check this dose with your clinician first.
MagnesiumRelaxes airway muscle. Magnesium given into a vein in the hospital for a severe attack is a different treatment and is not evidence for tablets; oral magnesium did not reduce reliever use or symptoms in trials4.Not recommended for asthma (trials found no change in symptoms or reliever use)Not applicableThe upper intake level for supplemental magnesium is 350 mg/day; above that, diarrhea is common. With kidney disease, take it only on your clinician's advice.
QuercetinEvidence in asthma comes from laboratory and animal studies; human studies are scarce16.500 to 1,000 mg/dayEmpty stomach (15 min before meals)Often combined with bromelain for absorption.
N-Acetyl Cysteine (NAC)Mucolytic, thins thick mucus. Glutathione precursor. Its trial evidence comes from COPD and chronic bronchitis; those reviews left out people with asthma13.600 to 1,800 mg/dayDivided dosesSulfur smell.
Vitamin CAntioxidant. May reduce exercise-induced bronchoconstriction. Antihistamine effects.500 to 2,000 mg/dayDivided dosesLiposomal forms easier on stomach. The adult upper intake level is 2,000 mg a day, and the body converts vitamin C to oxalate, so if you have had kidney stones, ask your clinician first.
Probiotics (Lactobacillus, Bifidobacterium)Studied for the gut-lung axis; evidence for reducing asthma severity is limited.10 to 30 billion CFU/day, multi-strainWith or without foodA 2026 review of 13 trials in adults found a small lung function benefit, not enough to justify routine use11.
Boswellia (Frankincense)Inhibits 5-⁠lipoxygenase (the same enzyme targeted by zileuton) in laboratory work, reducing leukotrienes. Anti-inflammatory.300 to 400 mg, 3x/day (standardized to 60% boswellic acids)With mealsWell-tolerated. The trial behind its use in asthma was small: 80 adults for 6 weeks14.

What to Expect Over Time

Prescribed preventer and reliever inhalers are the treatment; everything else on this page is added to them, never used instead.

Treatment and supportive care, together
First Weeks

A steroid preventer inhaler does not work right away: wheezing usually eases within 3 to 7 days of daily use, with the full benefit over several weeks23. Ask for an inhaler technique check and a written action plan15. Tell your clinician if you are no better after 7 days23.

Months 1 to 3

You should need the reliever less often23. In adults with obesity, weight loss over 12 to 24 weeks improved asthma control in trials22. Vitamin D did not reduce attacks in trials; correct a deficiency for general health only3.

Months 3 to 12

Keep taking the preventer when you feel well; stopping it suddenly can bring symptoms back23. The weight-loss benefit had faded by 52 weeks, so it lasts only while the weight stays off22.

Long Term

Asthma is often lifelong, though childhood asthma sometimes goes away. Have a checkup at least once a year covering inhaler technique and your action plan15.

When to Seek Care

Call 911 for an asthma attack if your reliever inhaler is not helping or you feel worse at any point, if you are too breathless to speak or are breathless at rest, if your lips or face turn blue, or if you become drowsy or confused24. After any attack, see your clinician within 2 days even if you feel better, and sooner if you need your reliever more often or symptoms wake you at night15.

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Better Control Is Possible

Take your preventer as prescribed, keep a written action plan, avoid your triggers, stay smoke-free and aim for a healthy weight15. No food or supplement replaces an inhaler. Better control often means needing the reliever less. Never discontinue prescribed asthma medications without medical guidance.

References & Evidence Notes

Each numbered entry below is either a source you can follow or a note setting out what the evidence does and does not support. Both are numbered together so the markers in the text line up.

Last reviewed October 20, 2026. Supplement entries are cross-checked against the NIH National Center for Complementary and Integrative Health and the Linus Pauling Institute Micronutrient Information Center.7 Never stop your preventer inhaler because you feel well. Inhaled corticosteroids work by suppressing the underlying airway inflammation, so feeling fine is what success looks like, and stopping them is a recognized contributor to fatal asthma attacks. Relying on a reliever (rescue) inhaler alone is no longer recommended. Know the emergency signs: inability to speak in full sentences, blue lips or fingertips, or a chest that has gone quiet because too little air is moving. Those mean emergency services immediately. Everything nutritional on this page works alongside inhalers, never instead of them.

  1. On inhaled corticosteroids. Asthma is an inflammatory disease, and inhaled corticosteroids treat the inflammation while short-acting beta-agonists only relieve bronchoconstriction. Global Initiative for Asthma guidance no longer recommends reliever-only treatment for adults and adolescents, because SABA-only management is associated with increased exacerbations and death, and because over-reliance on a reliever masks deteriorating control. Using a reliever more than about twice a week suggests inadequate control. ↩
  2. On recognizing a severe attack. Inability to complete sentences, use of accessory muscles, a respiratory rate that is climbing, exhaustion, cyanosis and a silent chest, where wheeze disappears because airflow is too poor to generate it, all indicate life-threatening asthma. A silent chest is more dangerous than loud wheezing, which is counterintuitive and is why it is worth knowing in advance. A written asthma action plan improves outcomes and should exist before it is needed. ↩
  3. On vitamin D: an earlier Cochrane review suggested that vitamin D supplementation reduced asthma attacks needing steroid tablets. Its 2023 update, with 20 trials in children and adults, found no reduction in those attacks, no improvement in asthma control and no difference by baseline vitamin D level, although profound deficiency was rare in the trials, PubMed 36744416. Correcting a deficiency is reasonable for general health; vitamin D is not a treatment for asthma. The adult tolerable upper intake level is 4,000 IU/day. ↩
  4. On other supplements and diet: magnesium is a bronchodilator and intravenous magnesium is used in emergency treatment of severe attacks, but that is a hospital treatment and is not evidence for tablets: a 2019 review of 8 trials in 917 people found oral magnesium improved one lung function measure at 8 weeks only, with no change in reliever use or symptoms, PubMed 30778086. Omega-⁠3 trials have been largely disappointing. A diet high in fruit and vegetables is associated with better asthma control observationally. Obesity worsens asthma control and weight loss improves it, which is one of the better-supported lifestyle levers. ↩
  5. On triggers and comorbidities: allergen exposure, respiratory infection, exercise, cold air, smoke and air pollution are common triggers. Aspirin-exacerbated respiratory disease affects a minority and matters because NSAIDs can precipitate severe attacks. Allergic rhinitis, reflux, obesity and obstructive sleep apnea all worsen control and are treatable in their own right. ↩
  6. On biologic therapy: for severe asthma, monoclonal antibodies targeting IgE, IL-⁠5 and IL-⁠4/13 substantially reduce exacerbations and oral steroid dependence in appropriately selected patients. Anyone requiring frequent courses of oral steroids should be assessed for these rather than continuing on repeated courses of prednisone, which carries substantial cumulative harm. ↩
  7. National Center for Complementary and Integrative Health (NIH), nccih.nih.gov, and the Linus Pauling Institute Micronutrient Information Center, lpi.oregonstate.edu/mic. ↩
  8. On breathing exercises: a 2020 Cochrane review of 22 randomized trials in 2,880 adults with mild to moderate asthma, covering Buteyko, yoga, Papworth and diaphragmatic breathing, found that breathing exercises may improve quality of life, hyperventilation symptoms and lung function, with evidence ranging from moderate to very low certainty, PubMed 32212422. ↩
  9. On confirming asthma with spirometry: the Global Initiative for Asthma 2025 summary guide lists significant bronchodilator responsiveness in adults as FEV1 or FVC increasing by 12% and by 200 mL from the pre-bronchodilator value, alongside other ways to show variable airflow such as peak flow variability over 2 weeks and a positive bronchial challenge test, ginasthma.org. ↩
  10. On asthma types: airway samples from 42 people with mild to moderate asthma split into two evenly sized groups by gene expression, Th2-⁠high and Th2-⁠low, with the Th2-⁠low group indistinguishable from healthy controls, PubMed 19483109. ↩
  11. On the gut and asthma: in four childhood cohorts, children given antibiotics in their first 3 years were more likely to develop asthma (odds ratio 2.18), an observed association, PubMed 28423467; and a 2026 review of 13 trials of probiotics, prebiotics or synbiotics in adults with asthma found a mild benefit on lung function, no significant change in asthma control scores, and concluded that the evidence does not justify routine use, PubMed 42614164. ↩
  12. On reliever-only treatment: the Global Initiative for Asthma strategy of 2019 stopped recommending treatment with short-acting bronchodilators alone for adults and adolescents, PubMed 31249014. ↩
  13. On N-acetylcysteine: a Cochrane review of 38 trials of oral mucolytics, including N-acetylcysteine, in chronic bronchitis or COPD found that more people stayed free of flare-ups on treatment, with smaller effects in longer and more recent studies. People with asthma were excluded, so the review does not show a benefit in asthma, PubMed 31107966. ↩
  14. On boswellia: a 6-⁠week double-blind trial in 80 adults with asthma, 40 given 300 mg of gum resin three times a day and 40 given placebo, reported improvement in 70% of the treated group against 27% on placebo; it is a small, short trial, PubMed 9810030. ↩
  15. On living with asthma: NHS guidance notes that the cause of asthma is not fully understood, lists allergies, a family history, prematurity or low birth weight, childhood smoke and pollution exposure, early chest illnesses, excess weight and chemicals at work among the risks, and warns that some painkillers and beta blockers can set off symptoms. It advises a written asthma action plan, a checkup at least once a year that includes inhaler technique, a flu vaccine, not smoking and keeping to a healthy weight, and seeing a doctor within 2 days of any attack even after recovering, NHS, asthma. ↩
  16. On quercetin: a 2025 review of quercetin in allergic disease reports that the support for its use in asthma comes from preclinical (laboratory and animal) studies, and that human studies are scarce, with only two clinical trials of quercetin alone across all allergic diseases, PubMed 40362785. ↩
  17. On curcumin: in a double-blind trial, 60 adults with non-allergic asthma took 40 mg of nano-curcumin three times a day or placebo alongside standard treatment for 60 days, and lung function, asthma control and quality of life did not differ from placebo, PubMed 38966624; a 2021 trial protocol describes the earlier results in asthma as limited and mixed, PubMed 34404358. ↩
  18. On how common asthma is in the US: CDC figures from the 2023 National Health Interview Survey estimate that 27.8 million people had current asthma, 8.4% of the population, including 23.0 million adults (8.9%) and 4.8 million children (6.7%), and national death records count 3,624 deaths from asthma in 2023, CDC, most recent asthma data. ↩
  19. On what asthma costs: an analysis of US national survey data for 2008 to 2013 put the total cost of asthma at $81.9 billion in 2013, made up of $50.3 billion in medical costs, $29 billion from deaths and $3 billion from missed work and school days, PubMed 29323930. ↩
  20. On asthma worldwide and what raises the risk: WHO estimates that asthma affected 363 million people in 2023 and caused 442,000 deaths. It lists a family history of asthma, other allergic conditions, low birth weight, prematurity, early exposure to tobacco smoke and air pollution, viral respiratory infections, house dust mites, molds, chemicals, fumes or dust at work, and overweight or obesity among the factors linked to asthma, and names inhaled medication as the treatment that controls it, WHO, asthma. ↩
  21. On smoke and asthma: NIH guidance states that smoking tobacco and breathing secondhand smoke make asthma harder to treat, and that vaping and secondhand vapor may also worsen symptoms, NHLBI, living with asthma. ↩
  22. On weight loss: a review of 6 randomized trials in 522 adults with obesity and asthma found that weight loss over 12 to 24 weeks improved asthma control, quality of life and lung function, most markedly in people who lost 10% or more of their weight, but the benefits were not sustained at 52 weeks, PubMed 41242610. ↩
  23. On how a preventer inhaler works over time: NHS guidance on steroid preventer inhalers says they do not work right away; people usually wheeze less or feel less breathless after 3 to 7 days, the full benefit can take several weeks, reliever use should fall as symptoms improve, a doctor or nurse should hear promptly if there is no improvement after 7 days, and stopping suddenly can bring breathing problems back, NHS, steroid preventer inhalers. ↩
  24. On when an attack is an emergency: US guidance advises going to the emergency room or calling emergency services at once for drowsiness or confusion, severe shortness of breath at rest, blue lips or face, extreme difficulty breathing or difficulty speaking, MedlinePlus, asthma; asthma charity guidance adds calling an ambulance if you feel worse at any point or your reliever does not help, Asthma + Lung UK, asthma attacks. ↩
  25. Gencer B, Djousse L, Al-Ramady OT, Cook NR, Manson JE, Albert CM. Effect of long-term marine omega-⁠3 fatty acids supplementation on the risk of atrial fibrillation in randomized controlled trials of cardiovascular outcomes: a systematic review and meta-analysis. Circulation. 2021;144(25):1981-⁠1990. PubMed 34612056. Seven trials with 81,210 people followed for about 5 years: omega-⁠3 supplements were linked to a higher risk of atrial fibrillation (hazard ratio 1.25), more so in trials of more than 1 g a day (1.49), and the risk rose with each additional gram. ↩
  26. On the Asthma Control Test: in a survey of 570 adults with asthma, the score that best separated well-controlled asthma was confirmed to be 20 or higher, and 15 or lower marked poorly controlled asthma, PubMed 18069909. ↩